obtained results | dissemination | involvement of young researchers | patents

Application patent: no. A/00742 / 22.09.2008

GEMOTHERAPY MOMORDICA CHARANTIA-BASED PREPARATION FOR THE TREATMENT OF NON-INSULINE-DEPENDENT DIABETES

IANCULOV IOSIF*, BOTĂU DORICA*, CIULCA SORIN*, PALICICA RADU–DIMITRIE*, LAZĂR ALEXANDRU*, HĂLMĂGEAN LUCIAN**, CRIŞAN SIMONA**

*Banat University of Agricultural Sciences and Veterinary Medicine Timisoara,
**Aurel Vlaicu University, Arad

The gemotherapy preparation for the treatment of non-insulin-dependent diabetes is based in its Hahnemian decimal dilution (DH 1) on hydro-glycerol-alcohol macerates from shoots and young twigs of Momordica charantia (bitter melon or bitter gourd).

Plante de Momordica charantia regenerate indirect, in conditiile culturii in vitro Plante regenerate, aclimatizate pentru cultivare normala – sursa de lastari tineri Momordica charantia cultura în câmp
The present invention concerns the development of a gemo-therapeutic preparation used in the treatment of non insulin-dependent diabetes, prime dilution solutions (DH 1) of hydro-glycerol-alcohol macerated from fresh vegetal extracts represented by meristematic tissues of growing Momordica charantia. In the development of this preparation we prepared a gemo-derivative from this plant since there are more substances and active principles in the germs, buds, and other embryo tissues than in the adult plant. Due to the growing factor content, the nutritious supply is particularly important. We used 5 g of fresh vegetal material for the extract, that we macerated for 7 days in 10 g of ethylic alcohol 900, then for another 21 in water and glycerine 1.1, the ratio dried vegetal material solvent being 1:20. We then filtered and diluted 1:10 with a mixture of water, alcohol and glycerine 2:3:5. At present, the gemo-therapeutic preparation is in clinical testing on animals (diabetic rabbits) with encouraging preliminary results.
Preparat gemoterapic din Momordica charantia

Application patent: no. A/00688 din 08.09.2009

MEDICAMENTARY COMPOSITIONS BASED ON IN VITRO CULTIVATED VEGETAL TISSUES FOR THE TREATMENT OF NON-INSULINE-DEPENDENT DIABETES

Botau Dorica*, Ianculov Iosif*, Sărăndan Horea*, Lazăr Alexandru*, Tudor Constantin**
*Banat’s University of Agricultural Sciences and Veterinary Medicine, Timisoara, ROMANIA
**Municipal Hospital Timisoara, ROMANIA

Medicamentary compositions for the treatment of non-insuline-dependent diabetes contain powder from in vitro selected vegetal tissues (callus) of some species with antidiabetic properties: Momordica charantia, Morus alba, Vaccinium myrtillus, Arctium lappa.

Calus de Arctium lappa Calus de Vaccinium myrtillus

Calus de Momordica charantia Calus de Morus alba
The present invention concerns the development of a medicamentary compositions used in the treatment of non insulin-dependent diabetes. These compositions contain vegetal tissue powders from plants with hypoglicemic properties: bitter melon, (Momordica charantia), white mulberry (Morus alba), blueberry (Vaccinium myrtillus) and burdock (Arctium lappa), which together operate an addition of pharmacodynamic action. The selected vegetal tissue from in vitro cultures (callus), under phitohormons, mineral and organic nutrients of artificial culture media, synthetize the specific active principles of plants in the large amount and these can be used succesfully to obtain pharmaceutic preparations as from whole plants.

Compoziţii medicamentoase pentru tratamentul diabetului non-insulino-dependent


Patent application nr. A00498 / 8.06.2010

OBTAINING PROCEEDING OF A HERBAL AND MUSHROOMS GEMOTERAPIC PREPARATION


Patent Application No. : A/00282 / 25.03.2010

PHARMACEUTICAL PREPARATION FOR DIFFERENT CANCER FORMS TREATEMENT